J.Technology and Education, Vol.32, No.2, pp.33-36 (2025)
研究論文

ポリ-L-グルタミン酸誘導体薄膜の構造解析と接触角評価

 

山本 華¹，川合 涼水², 高倉 克人²，山本 智代²，淀谷 真也^2*

¹鈴鹿工業高等専門学校・総合イノベーション工学専攻（〒510-0294 三重県鈴鹿市白子町官有地）

²鈴鹿工業高等専門学校・生物応用化学科（〒510-0294 三重県鈴鹿市白子町官有地）

*E-mail: yodoya@chem.suzuka-ct.ac.jp

 

Structural Analysis and Water Contact Angle Evaluation of Poly-L-Glutamic Acid Derivative Thin Films

 

Hana Yamamoto¹, Suzumi Kawai², Katsuto Takakura², Chiyo Yamamoto², and Shinya Yodoya^2*

¹Advanced Engineering Course of Science and Technology for Innovation, National Institute of Technology, Suzuka College.

²Department of Chemistry and Biochemistry, National Institute of Technology, Suzuka College.

(Shiroko-cho, Suzuka-shi, Mie 5100294, Japan.)

 

(Received September 1, 2025; Accepted October 10, 2025)

 

Poly-L-α-amino acids are structurally similar to natural proteins and exhibit excellent biocompatibility and biodegradability, making them attractive for biomaterial and eco-friendly applications. In this study, poly(γ-methyl-L-glutamate) (PMLG) and poly(γ-benzyl-L-glutamate) (PBLG) were synthesized from L-glutamic acid derivatives and processed into thin films. The films were characterized using field-emission scanning electron microscopy (FE?SEM) to examine surface and cross-sectional morphologies, and their wettability was assessed via water contact angle measurements. FE?SEM analysis revealed that, while surface morphology was largely unaffected by side-chain variations, internal structures differed significantly: PBLG films exhibited well-defined layered architectures, whereas PMLG films showed less-distinct layering. Contact angle measurements indicated that PMLG surfaces were hydrophilic, while PBLG surfaces were hydrophobic, reflecting the influence of side-chain chemistry on surface wettability. These findings demonstrate that the molecular design of poly-L-glutamic acid derivatives can effectively modulate both internal film structure and surface properties, providing valuable insights for the development of functional thin-film biomaterials.

Keywords: Poly-L-glutamic acid derivatives, thin film morphology, water contact angle, biomaterials