J. Technology and Education, Vol.29, No.1, pp.7-11 (2022)

研究論文

硫黄原子を含む極性基側鎖を導入したフタロシアニンの合成

 

渡辺 絢晴、松井 栄樹*

 

福井工業高等専門学校　物質工学科（〒916-8507　福井県鯖江市下司町）

*eiki@fukui-nct.ac.jp

 

Synthesis of phthalocyanines that have polar groups

containing a sulfur atom

 

Kensei WATANABE and Eiki MATSUI*

 

Department of Chemistry and Biology, National Institute of Technology, Fukui College

(Geshi, Sabae, Fukui 916-8507, Japan)

 

(Received March 18, 2022; Accepted April 11, 2022)

 

Abstract

In this study, we tried to develop new functionalized phthalocyanines (Pc1, Pc2) by introducing polar amino groups through carbon chains that contain a sulfur atom into the outside  of the phthalocyanines. Synthesis of these phthalocyanine compounds (Pcs) was carried out in two stages, and the formation of Pcs was confirmed by a UV-vis absorption spectrum and MALDI-MS measurement. We also confirmed their ability to dissolve in water and dilute an acidic aqueous solution. These results will help in the development of highly biocompatible phthalocyanine compounds for photodynamic therapy (PDT).

Keywords: Phthalocyanine, sulfur atom, water-soluble phthalocyanine, PDT